Sunday, February 5, 2023
News

New findings on neuronal activities in the sensorimotor cortex: Research

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

Washington | December 6, 2022 4:01:35 PM IST
An interdisciplinary research team at the University of Freiburg has found important clues about the functioning of the sensorimotor cortex. The new findings on neuronal activities in this brain area could be helpful for the further development and use of so-called neuroprostheses. These have an interface with the nervous system and are intended to help compensate for neuronal dysfunctions.

"Our results will contribute to the improvement of neuroprosthetic approaches while shortening the training period of patients with prostheses," says neurobiologist Prof. Dr. Ilka Diester from the Faculty of Biology at the University of Freiburg. The results have just been published in the journal Nature Communications.

The research project also involved the working groups of computer scientist Prof. Dr. Thomas Brox from the University of Freiburg and neuroscientist Prof. Dr. Daniel Durstewitz from the Central Institute of Mental Health in Mannheim. The team found evidence of conserved structures of neuronal activity in the sensorimotor cortex of freely moving rats. The electrophysiological recordings across the entire bilateral sensorimotor cortex allow conclusions about the respective contributions of the premotor, motor and sensory areas. In particular, the researchers found a clear gradient for a contralateral bias, i.e. for movements of the opposite half of the body, from anterior to posterior regions.

Previous findings on sensorimotor cortex are mostly based on highly constrained, stereotyped movements in a laboratory setting. The current work uses recordings on freely moving subjects using 3D tracking and addresses the question of the transferability of knowledge about neural control of movements from constrained behavior to a freely moving condition, a prerequisite for understanding the brain under more natural conditions as well as for the further development of neuroprosthetic devices.

The team used a dimensionality reduction and neural data alignment method. Thus, the high-dimensional neuronal patterns were reduced to a low-dimensional representation by means of their similarity to other patterns, resulting in geometric structures in the visual representation. These geometric patterns were then automatically aligned with each other, similar to the image of holding a magnet to a pack of nails. These then align themselves in a certain direction. Based on such aligned geometric structures, the researchers were able to decipher behavioral categories across recording sessions and even across individuals, and find corresponding evidence of conserved structures of neural activity. (ANI)

 
  LATEST COMMENTS (0)
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
 
MORE HEALTH NEWS
How chemotherapy drug delays enzymes tha...
Sudden cardiac arrest rare in older adul...
Research reveals preventative measures f...
Study finds coffee with milk can have an...
Study: Everyday well-being improved by g...
Impact of hyper-palatable foods revealed...
More...
 
INDIA WORLD ASIA
Congress' 'Haath se haath Jodo' programm...
'Scapegoats': Delhi court discharges 11 ...
Rs 9.4 lakh worth 'counterfeit' coins se...
J-K land subsidence: GSI team visits Dod...
'Instead of claiming credit, place files...
'Safeguard your MLAs', K'taka CM tells C...
More...    
 
 Top Stories
AAP Councillors write to MCD Presid... 
Pakistan: Soldier killed, seven inj... 
J-K: ADGP Kashmir reviews security,... 
ISL: Bengaluru FC's Sivasakthi wins... 
Protests in Bangladesh over China's... 
Assam to host first Youth20 Incepti... 
Zhu Lin triumphs over Lesia Tsurenk... 
I-League: Kasimov's strike helps NE...