Thursday, March 28, 2024
News

Weight fluctuations may increase health risks in adults with kidney disease

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

Washington | August 15, 2021 1:45:23 PM IST
A recent study has linked weight fluctuations--or body mass index variability--to higher risks of cardiovascular-related problems and early death in adults with chronic kidney disease (CKD).

The findings of the study appear in the journal 'JASN'.

Body mass index variability is associated with higher risks of developing heart conditions in the general population.

Because cardiovascular disease is the leading cause of death in individuals with CKD, a team led by Dong Ki Kim, MD, PhD, Sehoon Park, MD, and Kyungdo Han, PhD examined whether BMI variability may affect the prognosis of patients with kidney dysfunction.

The study included 84,636 patients with CKD who were listed in a national health screening database in South Korea. During a median follow-up of 4 years, 6 per cent of individuals died, 4 per cent needed kidney replacement therapy such as dialysis, 2 per cent suffered a heart attack, and three per cent suffered a stroke.

Compared with individuals with the lowest body mass index variability, those with the highest body mass index variability faced a 66 per cent higher risk of dying, a 20 per cent higher risk of needing kidney replacement therapy, a 19 per cent higher risk of experiencing a heart attack, and a 19 per cent higher risk of experiencing a stroke.

"This study showed that people who had kidney function impairment with recent fluctuating body mass index had a higher risk of cardiovascular disease or death, regardless of their current body mass index," said Dr Kim, of Seoul National University Hospital.

"This result suggests that people with kidney function impairment should pay attention to their fluctuating weight status, and those with fluctuating weight may benefit from receiving appropriate screening and risk factor management to prevent cardiovascular disease or progression of their kidney dysfunction," added Dr Kim.

The results were similar in the subgroups divided according to positive/negative trends in BMI during the exposure assessment period.

In addition, variabilities in certain metabolic syndrome components were also significantly associated with the prognosis of predialysis CKD patients.

Furthermore, those with a higher number of metabolic syndrome components with high variability had a worse prognosis.

Study co-authors include Semin Cho, MD, Soojin Lee, MD, Yaerim Kim, MD, PhD, Sanghyun Park, Yong Chul Kim, MD, PhD, Seung Seok Han, MD, PhD, Hajeong Lee, MD, PhD, Jung Pyo Lee, MD, PhD, Kwon Wook Joo, MD, PhD, Chun Soo Lim, MD, PhD, and Yon Su Kim, MD, PhD. (ANI)

 
  LATEST COMMENTS ()
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
 
MORE HEALTH NEWS
Study finds how childhood sedentariness ...
Longer genes are associated with ageing...
Dr. Dangs Lab aims to revolutionise heal...
Researchers find ways to reduce side eff...
Study gives insight into role of specifi...
Collaborative study between bariatric, t...
More...
 
INDIA WORLD ASIA
Centre extends AFSPA in 8 districts, 21 ...
Nanakmatta Gurudwara Kar Sewa Pramukh ki...
'Was working on the ideas of PM Modi': N...
'Don't have that kind of money to contes...
'Congress will win all 6 seats in by-ele...
'There is a huge wave for PM Modi in Tam...
More...    
 
 Top Stories
"CM should apologise to people of C... 
About 80,000 leaders, workers from ... 
Pakistan: Company halts work on pow... 
JISA Softech Secures MoU for Advanc... 
Lok Sabha polls: BJP holds core com... 
L'Oreal Professionnel brings Indian... 
"Government open to change in Agniv... 
PIL seeks seamless internet connect...