Wednesday, September 28, 2022
News
NEWS HOME
PRN INDIA
HIGHLIGHTS FROM THE ALZHEIMER'S ASSOCIATION INTERNATIONAL CONFERENCE 2022
  SocialTwist Tell-a-Friend  
   

SAN DIEGO, Aug. 3, 2022 /PRNewswire/ -- New research reported at the Alzheimer's Association International Conference (AAIC ) 2022 covered the breadth of Alzheimer's and dementia research, including the basic biology of aging and the brain, risk factors and prevention strategies, and caregiving and living well with the disease.

AAIC 2022

AAIC is the premier annual forum for presentation and discussion of the latest Alzheimer's and dementia research. This year's hybrid conference event took place both virtually and in-person in San Diego and attracted over 9,500 attendees and more than 4,000 scientific presentations.

"With record public and private research investment it's an exciting time for Alzheimer's and dementia research," said Heather M. Snyder, Ph.D., Alzheimer's Association vice president of medical and scientific relations. "Researchers are advancing our understanding of the disease by exploring biomarkers, discovering potential ways to reduce risk, and working to move promising treatments and diagnostic tools forward into clinical testing. The Alzheimer's Association is leading the fight through funding, convening, publishing, partnerships, advocacy and services."

Advances in Treatments, Clinical Trial Results

The Alzheimer's Association highlighted results from a variety of clinical trials at AAIC 2022. Encouraging and supporting a diverse treatment pipeline is essential to achieving the Association's vision of a world without Alzheimer's and all other dementia. Here are two examples:

The EXERT Study is the longest-ever Phase 3 study of exercise in older adults with mild cognitive impairment (MCI). The results, first reported at AAIC 2022, are especially noteworthy since the trial was conducted during the COVID-19 pandemic 80% of participants complied with their exercise regimen and completed the study. After 12 months, people with MCI in both the aerobic exercise intervention arm and stretching arm showed no cognitive decline. A comparison group of other older adults with MCI showed significant cognitive decline over 12 months. The findings from EXERT suggest that regular physical activity, even modest or low exertion activity such as stretching, may protect brain cells against damage.

At AAIC 2022, T3D Therapeutics reported positive interim results from their Phase 2 trial of T3D-959, which seeks to overcome insulin resistance in the brain and restore the brain's metabolic health. These encouraging preliminary results are a positive sign, and final results are anticipated in 2023. As understanding of the biological underpinnings of Alzheimer's expands, the opportunity to advance novel approaches such as T3D-959 will also expand.

Also at AAIC, the Alzheimer's Association announced the launch of the Alzheimer's Network for Treatment and Diagnostics (ALZ-NET), which will collect long-term clinical and safety data from patients treated with FDA-approved Alzheimer's disease therapies in real world clinical settings. ALZ-NET is the first network developed specifically for new FDA-approved Alzheimer's treatments, collecting evidence on effectiveness and side effects over a long period of time.

Experiences of Racism Associated with Poor Memory, Increased Cognitive Decline

Experiences of structural, interpersonal and institutional racism are associated with lower memory scores and worse cognition in midlife and old age, especially among Black individuals.

  • In a study of nearly 1,000 middle-aged community-dwelling adults (55% Latinx; 23% Black; 19% White), exposure to interpersonal and institutional racism was associated with lower memory scores; the associations were strongest in Black individuals. Experiences of structural racism were associated with lower episodic memory among all racial and ethnic groups included in the study.
  • In a study of 445 Asian, Black, Latino, White and multiracial people age 90 and above, individuals who experienced wide-ranging discrimination throughout life had poorer long-term memory in late life compared to those who experienced little to no discrimination.
History of Hypertensive Disorders During Pregnancy Linked to Increased Risk of Dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but before today, little research has connected these disorders with cognition. Experiences of high blood pressure disorders during pregnancy are associated with an increased risk of vascular dementia and accelerated brain aging, according to several studies at AAIC 2022:

  • Women with a history of HDP were more likely to develop vascular dementia — a decline in thinking skills caused by conditions that block or reduce blood flow to the brain — later in life, compared to women with non-hypertensive pregnancies.
  • Experience of HDP, specifically high blood pressure during pregnancy, was associated with white matter pathology, a predictor of accelerated cognitive decline, 15 years after pregnancy.
  • Women with severe preeclampsia had significantly higher levels of beta amyloid, an Alzheimer's-related brain change, as measured in blood compared to those with non-hypertensive pregnancies.
Persistent Loss of Smell Due to COVID-19 Closely Connected to Long-Lasting Cognitive Problems, and ICU Stays May Double Risk of Dementia in Older Adults

New insights into factors that may predict, increase or protect against the impact of COVID-19 and the pandemic on memory and thinking skills were revealed by multiple studies at AAIC 2022. A research group from Argentina found that persistent loss of the sense of smell may be a better predictor of long-term cognitive and functional impairment than severity of the initial COVID-19 disease. In a large study population from nine Latin American countries, experiencing a positive life change during the pandemic, such as more quality time with friends and family, reduced the negative impact of the pandemic on memory and thinking skills. Finally, hospitalization in the intensive care unit (ICU) was associated with double the risk of dementia in older adults, according to Rush Alzheimer's Disease Center in Chicago. These findings could be significant given the tremendous upsurge in ICU hospitalizations during the COVID-19 pandemic.

Ultra-Processed Foods May Speed Cognitive Decline

A study presented at AAIC 2022 finds that people who eat large amounts of ultra-processed foods have a faster decline in cognition. Researchers studied 10,775 people over eight years and found that high consumption (more than 20% of daily intake) of ultra-processed foods led to a 28% faster decline in global cognitive scores, including memory, verbal fluency and executive function. Ultra-processed foods go through significant industrial processes and contain large quantities of fats, sugar, salt, artificial flavors/colors, stabilizers and/or preservatives. Examples include sodas, breakfast cereals, white bread, potato chips and frozen "junk" foods.

Lower Socioeconomic Status, Persistent Low Wages Linked to Dementia Risk and Faster Memory Decline

Socioeconomic status (SES) — reflecting both social and economic measures of a person's work experience, and of an individual's or family's economic access to resources and social position — has been linked to both physical and psychological health and well-being. Socioeconomic deprivation, including neighborhood disadvantages and persistent low wages, are associated with higher dementia risk, lower cognitive performance and faster memory decline, according to several studies:

  • Individuals who experience high socioeconomic deprivation — measured using income/wealth, unemployment rates, car/home ownership and household overcrowding — are significantly more likely to develop dementia compared to individuals of better socioeconomic status, even at high genetic risk.
  • Lower-quality neighborhood resources and difficulty paying for basic needs were associated with lower scores on cognitive tests among Black and Latino individuals.
  • Compared with workers earning higher wages, sustained low-wage earners experienced significantly faster memory decline in older age.
  • Higher parental SES was associated with increased resilience to the negative effects of Alzheimer's marker ptau-181, better baseline executive function and slower cognitive decline in older age.
About the Alzheimer's Association International Conference (AAIC )

The Alzheimer's Association International Conference (AAIC) is the world's largest gathering of researchers from around the world focused on Alzheimer's and other dementias. As a part of the Association's research program, AAIC serves as a catalyst for generating new knowledge about dementia and fostering a vital, collegial research community.
AAIC 2022 home page: www.alz.org/aaic/
AAIC 2022 newsroom: www.alz.org/aaic/pressroom.asp
AAIC 2022 hashtag: #AAIC22

About the Alzheimer's Association

The Alzheimer's Association is a worldwide voluntary health organization dedicated to Alzheimer's care, support and research. Our mission is to lead the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. Our vision is a world without Alzheimer's and all other dementia . Visit alz.org or call 800.272.3900.

Logo - https://mma.prnewswire.com/media/1869584/AAIC22_purple_font_rgb_Logo.jpg

More News by PR Newswire India

GLOBAL STANDARD OF CARE SIGNIFICANTLY REDUCED DUE TO MENTAL HEALTH OF HEALTHCARE WORKERS

Vieworks to Showcase Industrial Cameras and Lenses at VISION 2022

Eviation's Alice Achieves Milestone with First Flight of All-Electric Aircraft

SAUDI ARABIA IS THE FASTEST GROWING TOURISM DESTINATION IN THE G20

Internet sensation Khaby Lame announced as QNB Group's Official FIFA World Cup Qatar 2022™ Brand Ambassador

GIGABYTE Launches Z790 Series Motherboards Supporting Dual-Generation Intel Processors

Deltek Research to Unveil Top Federal Contracting Opportunities for 2023

ViewSonic Unveils Industry-First Foldable 135" All-in-One LED Display Solution Kit

NEOM Tech & Digital Company steps into the future as 'Tonomus'

Global Fab Equipment Spending Forecast to Reach All-Time High of Nearly $100 Billion in 2022, SEMI Reports

Kohler India celebrates their 10th Year of Pecha Kucha in New Delhi, India

U.S. Soy Sustainability Assurance Protocol (SSAP) Certificates Can Now Be Transferred

CP KELCO PARTNERS WITH EXOPOLYMER TO BRING NEXT-GENERATION FUNCTIONAL BIOPOLYMERS TO MARKET

Old Mission Selects Solace to Support Rapid Growth of Business through Event-Driven Architecture

GIGABYTE Launches Four AMD X670 Motherboards for New Ryzen 7000 Processors

SRK Knowledge Foundation announces transformational partnership with The Global Network for Zero

LyondellBasell Announces Organizational Changes

HarperCollins India presents HAPPILY INSURED: Your Guide to Understanding Insurance and Leading a Stress-Free Life by Kapil Mehta

Hisense Unveils Its FIFA World Cup Qatar 2022™ TVC "Perfect Match" Ahead of Tournament

The 2022 4th "My China Story" International Short Video Competition Award Ceremony was held in Hangzhou, Zhejiang

Light up the festive season with 'Sale Dhamaka' on MSI's laptop range

GLOBAL LEADERS, EXPERTS, AND CULTURAL ICONS CONVENE AT THE MILKEN INSTITUTE ASIA SUMMIT TO CELEBRATE A TRANSFORMED WORLD

Bank of Baroda rolls out 'Khushiyon ka Tyohaar' as the Festive Season begins

XCMG New Port Machinery's High-end Intelligent Industrial Development Project Base Launches Production

NATIONAL INSTITUTE FOR HEALTH AND CARE RESEARCH CONDUCTS A GLOBAL ANNUAL MEETING TO ADDRESS RESEARCH IN SURGERY IN INDIA

DEAKIN UNIVERSITY HUBS to be set up in India at OP Jindal Global University, Symbiosis International University and Chitkara University

TargEDys and Inoliva announce they have entered a distribution partnership to bring Satylia® to Turkey

Top 50 Start-ups Bringing Innovation to the Global Homes and Buildings Industry

How Healthcare Organizations Can Enhance a Holistic Patient and Member View by Improving Insights from Data

Tata AIA Life Fortune Guarantee Pension gets a powerful upgrade

PDRL aims to certify 10,000+ candidates on AeroMegh Platform in the Drone Industry by the year 2024

DAZN ACCELERATES GLOBAL GROWTH MOMENTUM WITH ACQUISITION OF ELEVEN GROUP BUSINESSES

GoingZero Big Diwali Sale: Up to 40% Discount And Free Shipping On Zero Waste Products

Slow-fashion brand FREECULTR becomes the official merchandise partner for FIFA 2022™

Purple Quarter Facilitates HCAH's CTO, Ex-DealShare Techie Onboarded

Ghodawat Consumer awarded - Fastest growing FMCG Company of 2022

Cine Star Cricket League launched with television and entertainment industry's Divas

ELLE FANNING IS THE AMBASSADOR OF FAME, PACO RABANNE'S NEW FEMININE FRAGRANCE

Saudi Data, AI Authority (SDAIA) and Ministry of Energy Partner with IBM to Accelerate Sustainability Initiatives in Saudi Arabia Using AI

Unstoppable Women of Web3 Launches New Education Streams

PNAS Partners with Straive for Production Services

MOBILEUM convenes the region's leading telecom operators at WEMEET ASIA 2022

Bizverse has officially become a Meta long-term strategic partnership

STL divests IDS as a part of its ongoing portfolio realignment

Frost & Sullivan Honors Tampa Electric Company and Warren, Simpson & Butler County Water Districts with Itron Excellence in Resourcefulness Awards

Mindray Showcases Hematology Innovations and Academic Achievements to the World at ISLH 2022

Deepak Chopra & Seva.Love Announce "ChopraVerse: House of Enlightenment," the Metaverse for Wellbeing in Collaboration with Utopia

MSC TO DEVELOP AIR CARGO SOLUTION IN RESPONSE TO MARKET DEMAND

Harpercollins is proud to announce the upcoming release of The Anarchist Cookbook: A Toolkit to Protest and Peaceful Resistance by Aakar Patel Illustrations by PenPencilDraw

Saudi Arabia launches Nusuk, an integrated digital platform, to facilitate pilgrim journeys for visitors from around the world

MEIL's wholly owned subsidiary MeghaGas, now MCGDPL, to execute City Gas Distribution

Yabx emerges as a leader in digital lending platforms at the top Global Fintech Awards

FII Institute reveals the world's top priority is the rising cost of living

All about IBSAT - One of the Top MBA Entrance Exams in India

MAPIC India 2022 honors India's most admired retail and tech innovators at the MAPIC India Retail Awards

Hasiru Dala Innovations joins forces with Satma CE to give immutable waste traceability from collection to final product made from waste

Bank of Baroda launches Baroda Tiranga Deposits

Alicon Castalloy Limited wins large, multi-year order from Jaguar Land Rover for eMobility Platform

mCaffeine's Biggest Body Care Launch Gets an Overwhelming Response from the Audience: 1 Consumer Subscribed Every 3 Seconds for the Launch

On World Lung Day, Alkem Laboratories pledge to spread awareness about lung diseases through its initiative 'The Healthy Lungs'

LONGi is to showcase its award-winning Hi-MO 5 Series at the Renewable Energy India Expo 2022, unveiling its new Hydrogen Business exclusively for Indian customers

LEXUS INDIA ANNOUNCES MENTORS FOR THE LEXUS DESIGN AWARD INDIA 2023

Mane Kancor CEO Geemon Korah hailed as one of the best CEO's in India

SVKM's NMIMS signs an MoU with HTWG Konstanz, Germany, for short study and research

Top HR Chiefs from TTK Prestige, Silicon Labs, Virtusa, Bureau Veritas at Woxsen's Global HR Leadership Conclave 2022

Mastercard expands decades-long football legacy through GUINNESS WORLD RECORDS™ title with Luis Figo

Soroco and Whatfix Announce Strategic Partnership

ElevenEs produces a prototype of the largest LFP battery cell in Europe

SHEIN CELEBRATED "ROCK THE RUNWAY: SHEIN FOR ALL", ITS FW22 FASHION SHOW

Huawei Hosts the 9th Global Rail Summit in Berlin

Campus With A Conscience hosts a-week long SDG festival

Woxsen University spearheading the internationalisation of higher education in the region through brand new initiatives

 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
INDIA WORLD ASIA
Study finds whether stress can actually ...
20 ministers, MLAs meet Gehlot...
BJP rally to Nabanna: HC asks Bengal gov...
Abu Salem gets three-year term in fake p...
ED takes action against online gaming ap...
Calcutta HC cautions Bengal Home Secy of...
More...    
 
 Top Stories
FAIMA writes to AIIMS director over... 
3rd ODI: India A hammer New Zealand... 
KCR will play key role in shaping c... 
Over 8 lakh viewers watched SC's fi... 
Pak-US ties no longer hyphenated wi... 
Delhi court grants bail to MCD offi... 
R'than crisis: Cong serves show-cau... 
National Games: Haryana, Bihar, Odi...