Monday, February 18, 2019
News
NEWS HOME
PRN INDIA
Canadian Scientist Positioned to Advance Groundbreaking Treatment for Leading Cause of Vision Loss
  SocialTwist Tell-a-Friend  
   

TORONTO, Oct. 11, 2018 /PRNewswire/ -- The Canadian scientist Dr. Andras Nagy, Senior Investigator at Mount Sinai's Lunenfeld-Tanenbaum Research Institute, is announced today as the inaugural recipient of the Cedric Ritchie Fund to Cure Blindness, a new $1.5 million initiative made possible by the Foundation Fighting Blindness, Canada's largest charitable funder of vision research.

Logo - https://mma.prnewswire.com/media/767801/Foundation_Fighting_Blindness.jpg

The Foundation Fighting Blindness - Canada is proud to launch the Cedric Ritchie Fund to Cure Blindness on World Sight Day, a day that raises awareness about the 253 million people around the world who are living with a severe vision impairment or blindness.

A pioneer in the field of stem cell research, Dr. Nagy has been studying the intricacies of stem cells for thirty years and is world-renowned for discovering a method to create stem cells from other cells in the body, a breakthrough in regenerative medicine. "In many ways this is the culmination of decades of work," said Sharon Colle, President and CEO of the organization awarding the grant, the Foundation Fighting Blindness - Canada. "Dr. Nagy is leveraging years of experience and research to develop a revolutionary approach to treating age-related macular degeneration (AMD), the leading cause of vision loss in people over the age of 50. Dr. Nagy aims to cure AMD by combining approaches in stem cell and gene therapy, two of the most promising therapeutic strategies in vision science."

"Our hope," continued Colle, "is that this grant will enable him to transition his approach out of the lab and into clinical trials, where it can be tested as an experimental treatment for people living with AMD. It's a journey that will take five years, a very short period within the often-plodding timeframes of scientific discovery." Clinical trials are an essential step in the development of potential treatments, and many scientists struggle to get that far. "Some refer to the gap between the lab and clinical trials as 'the valley of death,'" said Colle. "It's where excellent but poorly funded science goes to die. Considering what's at stake in Dr. Nagy's work, we couldn't let that happen."

Approximately 1.4 million Canadians are affected by AMD, and though treatment options exist for those with its most severe form, "wet-AMD," these involve frequent ocular injections of "anti-VEGF" drugs. "VEGF" refers to "vascular endothelial growth factor," an essential protein responsible for stimulating the growth of new blood vessels. In AMD, VEGF is overexpressed, leading to irregular blood vessel growth and, when left untreated, the leakage of blood into the eye—the "wet" in "wet-AMD."

"We're now able to genetically program stem cells to deliver anti-VEGF proteins on their own," explained Dr. Nagy. "It's a cutting-edge realization of the dream of regenerative medicine: rather than inject the protein into the patient's eye, we program stem cells to do the work for us. An added benefit, and one with enormous potential, is that these stem cells could also replace the retinal cells that are damaged in advanced AMD, restoring vision for patients who have lost it."

"This is an important stage," continued Dr. Nagy, "in the decades-long quest to treat a disease that robs far too many of their sight. Laser surgery was the only option decades ago, then photodynamic therapy emerged as a viable means for removing abnormal blood vessels, and more recently anti-VEGF injections became the standard of care. But I really think that combining stem cells with gene therapy is the next step: it's a new paradigm, a 'one-shot' therapy or cure that treats the condition while reversing vision loss, all without subjecting patients to regular discomfort and the barriers associating with repeated injections."

"The advancement of this work would have been impossible without support from the Foundation Fighting Blindness," said Dr. Nagy. "In Canada, funds earmarked for science are dwindling rapidly, so connecting individual donors to the best science possible has never been more essential." The $1.5 million initiative is the result of an individual commitment from Barbara Ritchie, whose late husband, Cedric Ritchie, lived his final years without sight due to complications from AMD and glaucoma. Mr. Ritchie was a renowned entrepreneur and Canadian banker who rose from teller, then president and CEO, and finally to chairman of the Bank of Nova Scotia. "Cedric never let vision loss get in his way," said Mrs. Ritchie, "and insisted on getting work done, regardless of the difficulty. I know that if he were here today, he'd want a similar principle applied to Canada's vision science. He'd want the best science to be supported, and he'd want it maximized to impact as many people as possible."

Contact Information: April Watts, Communications Manager, The Foundation Fighting Blindness – Canada, 1.800.461.3331 ext. 231, awatts@ffb.ca





More News by PR Newswire India

Pivotal Phase III Data for BAVENCIO® (avelumab) Plus INLYTA® (axitinib) in Advanced Renal Cell Carcinoma Published in the New England Journal of Medicine

Kochava Announces Latest Enhancements to IdentityLink, Giving Marketers a Clearer View of Their User Journeys

Battery Manufacturers to Integrate Energy Intelligence into Storage Systems to Tap Growth Opportunities

EB-5 February 15th Update: What Investors can Expect for the Future of EB-5

Rivian Announces $700M Investment Round Led By Amazon

OPPO's Gradient Design and Panoramic Screen Redefine Smartphone Experiences

JTI Awarded Top Employer for the 5th Consecutive Year

MORE - A Unique Hospitalisation Health Insurance Plan From Reliance Health Insurance

Schneider Electric Puts Control of Power distribution in Digital Devices; Launches Masterpact MTZ in India

Cyient Recognized as a "Major Contender" in Everest Group's PEAK Matrix™: Medical Device Engineering Services Assessment 2019

TÜV SÜD Receives Accreditation From Quality Council of India to Certify Ready Mixed Concrete Plants

ISABS: Personalized Medicine Conference With Nobel Laureates to Be Held in Split, Croatia

Global Business Summit to Address Challenges of a World in Transition

Sterlite Power Forays Into Grid Connected Battery Storage

Firefox for iOS Amps Up Private Browsing and More

Australia's First Kafnu To Open in Sydney

Singular Announces Global-First Cross-Device, Cross-Platform ROI Analytics

FastMatch And Former CEO, Dmitri Galinov, Confirm Settlement Agreement

The Stars Group Recognized With Industry Honors

Prozone Intu's Consolidated Revenues up 20% y-o-y to INR 33.9 Crore

New Milestone Reached With More Than 500 Dolby Atmos Screens Installed and 500 Dolby Atmos Titles Released in India

Thailand's Promotion of Advanced Technology and Eco-system Development Enables Local Producers to Fly Higher

OPPO is Set to Redefine its Design Statement With its #OPPOF11Pro Campaign

TÜV SÜD Showcases its SFDA and Halal Certification Capabilities at Gulfood

Perpule Launches UltraPOS, an Omni-channel Retail Solution, With Marquee Customers

Beijing Intellectual Property Court Confirms Judgment Against Wuxi Hisky Medical for Patent Infringement of Technology Used for Echosens' FibroScan®, Imposes Damages & Orders Halt to Manufacturing and Sales

UST Global Launches True Private Cloud Platform 'UST FORTUNA'

IIIT-Hyderabad Opens Admissions to its Undergraduate Programs for the Academic Year 2019-20

Saksoft Limited: 9MFY19 Revenues at Rs. 264 Crs, a Growth of 27% Y-o-Y

Mr. Binish Chudgar Wins the EY Entrepreneur of the Year 2018 Award in Life Sciences & Healthcare Category

Strata Celebrates Grand Opening of New Manufacturing Facility in India

MEIL's Innovation in Irrigation

ResellerClub Turns 13, Celebrates With Big Birthday Bash Sale on Hosting and Domains

Orthonova Hospital Performs Hip Replacement Surgery on 110 Years Old Lady

Frost & Sullivan Publishes Q1 2019 Update on Oramed Pharmaceuticals Inc.

16 Longevity Scientists Have A Valentine's Day Message For The World

Aon Releases 2019 Cyber Security Risk Report: "What's Now and What's Next"

Io-Tahoe releases enhanced Smart Data Discovery solution, with PII and Sensitive Data Discovery capability, enabling compliance with the California Consumer Privacy Act (CCPA)

Vidsys Recognized by Frost & Sullivan for its Comprehensive Converged Security Information Management System, RiskShield Enterprise

Prepare your Business for Digital Era to Transform Industrial Valves and Actuators Market

Auto Insurers Seize Growth Opportunities by Offering Financial and Insurance Tools over Digital Platforms

Suning.com Announced the Establishment of Department Store Group to Accelerate Its Full-Scenarios Development in Omni-channel Smart Retail

Medvarsity Online Ltd. Awarded as the Best Medical Institute in India at 9th Indian Education Awards 2019

Tableau Expands Data Prep Capabilities with Tableau Prep Conductor

JET8 Launches World's First Social Wallet

India Pharma Week 2018: Strengthening the Pharma Ecosystem in the Power Corridors of the North

Tableau Releases Ask Data, A New and Intuitive Way to Analyze Data With Natural Language

WCG Releases New Theme Song, Beyond the Game (Steve Aoki Remix)

FLAME University's Entrepreneurship Centre all Set to Catalyze the Indian Startup Ecosystem

Mumbai Recorded Gross Absorption of 2.1 Million sq ft in Q4 2018, Registering an Increase of 5.7% QoQ: Colliers International India

Kolkata Recorded Overall Absorption of 215,500 sq ft in Q4 2018: Kolkata Recorded Overall Absorption of 215,500 sq ft in Q4 2018: Colliers International India

IHG® Welcomes Six Senses Hotels Resorts Spas to its Family of Brands

Hyderabad Witnessed Gross Absorption of 6.8 Million sq ft in 2018, Highest in the Last Eight Years: Colliers International India

Letstrack CEO Named as India's Inspirational Leader by WCRC

Chennai Recorded 3.9 Million sq. ft. of Gross Leasing in 2018, a Decline of 18% From the Previous Year: Colliers International India

Fractal Analytics Hosts its First Conference in London to Help FTSE 250's Solve Problems at Scale Through AI, Engineering and Design

Manpasand Beverages Ltd Announces Q3 & 9MFY19 Results

HITLAB Innovators Summit: India Assembles Leaders Across Healthcare Ecosystem to Bring Meaningful Innovation to Over a Billion Lives

VARTA Applauded by Frost & Sullivan for its Smart, Scalable Residential Battery Storage Systems

India Biggest Obstacle Running Event, Maruti Suzuki Arena Devils Circuit - Jaipur Edition, Concludes

Intuition Systems Introduces Cloud-based IVEPOS Enterprise® With Multi-store Management for Large Restaurants and Retail Enterprises With up to 100 Stores

Essence wins integrated media duties for online higher education platform UpGrad in India

Pennar Industries Reports 34% y-o-y Increase in Q3 FY2019 Standalone PAT at INR 11.5 crore

Texas Cardiac Arrhythmia Institute at St. David's Medical Center first in U.S. to treat patient in study to evaluate balloon ablation catheter for treating Atrial Fibrillation

Novartis leverages digital transformation to address most pressing health challenges in Asia

Smiths Detection to greatly improve security and passenger experience at Northern Territory airports

IBM Announces Additional $25 Million Investment to Put Technology to Work Saving Lives

Jay Lang Appointed President Of Charkit Chemical

Colt Data Centre Services Appoints Sujeet Deshpande as New Country Head in India

Largest Study Of Mobile Ad Networks Ranks Facebook, Google, Snap, Twitter, Unity … And New Players

Frost & Sullivan Publishes Immediate Report on BiolineRx

IBM Unveils New Offerings for Faster and More Secured Path to Hybrid Cloud

IBM Watson Now Available Anywhere

CGTN America Receives 28 Awards in The White House News Photographers Association 2019 'Eyes of History' Video Contest

Adjust Raises the Bar With a New Industry Standard in the Global Fight Against Mobile Ad Fraud

Blockchain, Augmented Reality and Virtual Reality Highlighted as Emerging Trends at Frost & Sullivan's 2019 ICT Predictions Road Show

GTPL Hathway's Consolidated Q3 FY2019 Revenue at ₹ 3,199 Million, up 13% Y-o-Y

Firmenich CEO in Global Top 100 C-Suite Ranking

IBM Commended by Frost & Sullivan for Its Strong Managed Service Offerings in the Business-critical ERP Services Market

Loadsmart's Automated Freight Brokerage System Awarded Company of the Year by Frost & Sullivan

Kore.ai Earns Acclaim from Frost & Sullivan for its Visionary Conversational AI Platform that Helps Create Intelligent Financial Enterprises

Bill and Melinda Gates Release 2019 Annual Letter: "Things We Didn't See Coming"

Avon appoints Kay Nemoto as Chief Strategy and HR Officer to drive transformation

CORRECTION - Indo Amines Limited: Indo Amines Limited Declares a Robust Financial Growth Revenue at Rs. 120.16 Crs; EBITDA Stood at Rs. 16.09 Crs; PAT Reported at Rs. 6.88 Crs

Microland Positioned as a Major Contender in Everest Group's Cloud Enablement Services PEAK Matrix Assessment

Lincoln Electric System Partners with energyOrbit to Automate Management of Energy Efficiency Programs

Organica Water Selected for the 2019 Global Cleantech 100 list

Digital Transformation to Advance Global Airlines' Growth Prospects

GO GABA Founder Launches Campaign Iwantmybusinessback.com to Raise Awareness for Entrepreneurs

UNISOC Collaborates with Google to Carry out GMS Certification, Shortening the Time to Market for Mobile Devices

Singing app of Spotlite employs robots as judge for online games

SPJIMR’s PGMPW Receives AMBA’s ‘MBA Innovation Award’

/Disregard Release: S.P. Jain Institute of Management & Research: SPJIMR’s PGPMW Receives AMBA’s ‘MBA Innovation Award’/

Falabella Group and ThoughtWorks Partner to Accelerate the Digital Commerce Journey of Latin America’s Leading Integrated Retail Brand

Discover The World 'On The Go' With SOTC's Newly Launched Portal

A New Year, A New Beginning, A New Office for 42Gears

InComm Launches Google Play Gift Cards in Malaysia

DigitalBerge, The #1 SEO Company in Delhi NCR, Launches its Personal Branding Services

AACSB's Accreditation Quality Management System Achieves ISO 9001:2015

HMC Launches Centara Privilege - Providing Members in Thailand with Personalized Benefits and Recognition

SBI Neo Financial Services and AntWorks™ Announce Joint Venture to Provide Intelligent Automation to ASEAN Market Through SBI Antworks Asia

Growatt Donates Inverter to Indore Cancer Foundation's Rooftop Solar Plant Project

FDA Accepts sBLA and Grants Priority Review for BAVENCIO® (avelumab) Plus INLYTA® (axitinib) for the Treatment of Advanced Renal Cell Carcinoma

IBM Chairman, President And CEO Ginni Rometty To Keynote IBM Think 2019

The XXI Habanos Festival Kicks Off

Frost & Sullivan Webinar Explores What's Driving the Global Automotive Industry in 2019

National Geographic and Sky Ocean Ventures Launch Global Search for Alternatives to Single-Use Plastics

Prime Minister Shri Narendra Modi Laid Foundation Stone for Bio-refinery Project in Assam, a Collaboration of NRL, Fortum and Chempolis

SPJIMR’s PGPMW Receives AMBA’s ‘MBA Innovation Award’

Use of Big Data Technology in Cybersecurity Solutions to Help Enterprises Proactively Prevent Breaches

Viamedici Acclaimed by Frost & Sullivan for its Comprehensive Viamedici EPIM Platform for Data Management

Indo Amines Limited Declares a Robust Financial Growth Revenue at Rs. 120.16 Crs; EBITDA Stood at Rs. 16.09 Crs; PAT Reported at Rs. 6.88 Crs

"Thailand Investment Year" Sets to Accelerate Economic Shift and Boost Economic Growth

Johnson & Johnson India Shows Support to the LGBTQ+ Community, Participates in the Queer Azaadi Mumbai (QAM) Pride March

DLF Shopping Malls Celebrate a Decade of Retail Excellence

Privatisation a catalyst to unlock Eskom's true value potential

PIOUS AYURVEDA Announces Release of its Revolutionary Book 'SAVE YOUR HEADMASTER'

Coconics Unveils its First Range of Laptops at the Electronics Manufacturing Summit 2019 in Delhi

Kirti Mandir in Barsana Opens in a Grand and Historical Opening Ceremony

Flamingo Transworld Scoops 8 Awards at the Gujarat Tourism Awards 2018

IMA Releases Enhanced Management Accounting Competency Framework for Professionals in the Digital Age

Dr Batra's Homeopathy Offers Free Preventive Doses for Swine Flu Across Jaipur, Delhi, Chandigarh, Ahmedabad and Hyderabad

Red Box Announces Partnership With Global Relay, Expanding Its Financial Services Ecosystem and Compliance Offering

NirvanaBeing Announces a 20% Discount on Mace Pepper Spray

Tufin Appoints Michael Bosnar to the Position of Vice President of Asia-Pacific Sales

BATTERY JAPAN 2019: Solid-state battery and EV battery imminently set for commercialisation

WIND EXPO 2019: Industry leaders gather in Japan at the dawn of emerging offshore wind power

Japan's business continues to look bright at PV EXPO & PV SYSTEM EXPO 2019

STRATACACHE Centralizes Asia-­Pacific Operations in New Singapore Headquarters

Japan Rock Band CHAI Partners with PicsArt, #1 Photo & Video-Editing App, to Creatively Engage with Fans

Vivo Unveils New Visual Brand Identity

The Sunhak Peace Prize for 2019 Convened in Seoul Awarding Akinwumi Ayodeji Adesina & Waris Dirie

 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
INDIA WORLD ASIA
One jawan injured in encounter with Naxa...
Ahead of polls, YSRCP chief Jagan Reddy ...
J-K: Encounter between security forces a...
Odisha CM lays foundation stone for Canc...
Hyderabad gets its first Trompe-loeil a...
2 Youth Cong workers hacked to death in ...
More...    
 
 Top Stories
Poland PM cancels Israel trip after... 
9 dead in Boko Haram attack in Nige... 
Odisha CM lays foundation stone for... 
Mike Posner stays silent to preserv... 
Iran summons Pak envoy over suicide... 
J-K: Encounter between security for... 
Assad says Syrian constitution not ... 
Ahead of polls, YSRCP chief Jagan R...