Friday, May 20, 2022
News

Why Neanderthals never had brain disorders

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

Washington | Sunday, 2014 1:36:05 PM IST
In a significant discovery, scientists have found why modern humans develop brain disorders like autism or schizophrenia but our ancestor Neanderthals did not.

They have discovered the cellular equivalent of "on/off" switches that determine whether DNA is activated or not.

Hundreds of Neanderthals' genes were turned "off" while the identical genes in today's humans are turned "on".

Alternatively, hundreds of other genes were turned "on" in Neanderthals but are "off" in people living today.

The genes related to autism, as well as to schizophrenia and Alzheimer's disease, were more likely to be "off" in Neanderthals than in modern humans, said lead author Liram Carmel from Hebrew University of Jerusalem.

The discovery underlines the power of the "on/off" patterns.

The 'on/off' switches could also explain the anatomical differences between archaic and present-day humans, including Neanderthals' shorter legs and arms, bow-leggedness, large hands and fingers, and curved arm bones, Carmel explained.

When dozens of brain-related genes became more active in today's humans, that produced the harmful side effect of neurological illnesses, the study noted.

One person's genome can vary markedly from another's due to diet, environment and other factors.

It is, therefore, impossible to know whether the 'on/off' patterns found in Neanderthal genes are typical of the species overall or peculiar to the individual studied, the study, published in the journal Science, concluded.

-Indo-Asian News Service mak/na/rr/vt

( 234 Words)

2014-04-20-13:22:19 (IANS)

 
  LATEST COMMENTS (0)
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
 
MORE SCIENCE NEWS
NASA's Marsquake hunting mission to last...
Edtech platform Vedantu lays off 424 mor...
How exhaust pollution from SpaceX, Blue ...
Researchers reveal major infrared breakt...
Reseachers finds imbalance between energ...
Here's how greenhouse gas emissions can ...
More...
 
INDIA WORLD ASIA
Centre to deploy additional forces in Pu...
Partha Chatterjee approaches SC, matter ...
PM Modi to visit Tokyo to attend Quad Su...
Goa Assembly to conduct training for new...
Two incidents of stone pelting at Dalit ...
Sugar exports 15 times higher in 2021-22...
More...    
 
 Top Stories
Sri Lanka PM appoints former Maldiv... 
R Madhavan's biographical drama 'Ro... 
Balochistan: Give Rights campaign t... 
'Double-digit wholesale inflation t... 
No lessons learnt, Delhi continues ... 
Rahul leaves for UK to address Camb... 
'Right man in right party', Amarind... 
Parents proud as Nikhat Zareen brav...