Saturday, April 20, 2019
News

Researchers identify gene to treat alcoholism

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

New York | Saturday, 2019 4:15:06 PM IST
Researchers have identified a gene that could provide a new target for developing medication to prevent and treat alcoholism, according to a new study on mice.

Researchers at Oregon National Primate Research Center (ONPRC) in the US discovered a gene that had lower expression in the brains of non-human primates which voluntarily consumed heavy amounts of alcohol compared to those that drank less.

Furthermore, the team unraveled a link between alcohol and how it modulates the levels of activity of this particular gene.

Researchers discovered that when they increased the levels of the gene encoded protein in mice, they reduced alcohol consumption by almost 50 per cent without affecting the total amount of fluid consumed or their overall well-being.

The study modified the levels of the protein encoded by a single gene known as GPR39.

The prevalence rates of co-occurring mood and alcohol use disorders are high, with individuals with alcohol use disorder being 3.7 times more likely to have major depression than those who do not abuse alcohol.

Using a commercially available substance that mimics the activity of the GPR39 protein, the researchers found that targeting this gene dramatically reduced alcohol consumption in mice, showed the findings of the study published in the journal, Neuropsychopharmacology.

"The study highlights the importance of using cross-species approaches to identify and test relevant drugs for the treatment of alcohol use disorder," noted senior author Rita Cervera-Juanes, Research Assistant Professor at ONPRC.

--IANS pb/arm/ab

( 250 Words)

2019-02-09-15:52:06 (IANS)

 
  LATEST COMMENTS ()
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
 
MORE HEALTH NEWS
Adhesive patch to reduce heart attack da...
Study warns of measles outbreak...
Behavioural disorders in autistic kids l...
Pregnant women feel pushed out of their ...
More deaths likely to occur in Asian cou...
'Mental Hai Kya?' draws psychiatrists' i...
More...
 
INDIA WORLD ASIA
Sadhvi Pragya makes controversial Karkar...
No unanimity yet in Congress on AAP tie-...
Rohit Tiwari murder: Police say probing ...
PIL filed in Allahabad HC against Congre...
Sadhvi Pragya apologises for Karkare cur...
Kushwaha to remain RLSP chief till polls...
More...    
 
 Top Stories
BJP will get more seats than in 201... 
US: Right-wing militia detaining mi... 
Chinese national found dead in Paki... 
Pakistan FM to visit Japan... 
Trump recognises Haftar role in fig... 
26/11 response would have averted P... 
Deve Gowda was a much better PM tha... 
Kohli ton helps RCB beat KKR despit...