Monday, October 14, 2019
News

Infants' gut bacteria can help combat food allergy: Study

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

New York | Friday, 2019 2:15:04 PM IST
Healthy infants have intestinal bacteria that can prevent the development of food allergies, research has found.

Researchers from the University of Chicago, Argonne National Laboratory and the University of Naples Federico II in Italy transplanted gut microbes from each of eight infant donors: four healthy and four with cow's milk allergy, into groups of mice via fecal samples, Xinhua news agency reported.

The mice had been raised in a completely sterile, germ-free environment, and were fed the same formula as the infants to help the bacteria colonise properly by providing the same sources of nutrients.

The results show that mice receiving bacteria from allergic infants suffered from anaphylaxis -- a life-threatening allergic reaction, when exposed to cow's milk for the first time.

Germ-free control mice that were not given any bacteria also experienced this severe reaction.

However, those that received healthy bacteria appeared to be completely protected, and did not suffer an allergic reaction, the report said.

"What we see with this work is how, in the context of all of the different types of microorganisms inhabiting the gastrointestinal tract, one single organism can have such a profound effect on how the host is affected by dietary components," said Dionysios Antonopoulos, Assistant Professor at Argonne.

"We also get a new appreciation for the distinct roles that each of these members play beyond the generalisation that the 'microbiome' is involved," Antonopoulos added.

These bacteria or their metabolites could be used as part of biotherapeutic drugs to prevent or reverse other common food allergies, the researchers noted in the paper published on The Forefront.

The researchers also studied the composition of microbes in the intestinal tract of the mice and analysed differences in gene expression between the healthy and allergic groups, and this allowed them to pinpoint a particular species, Anaerostipes caccae, that appears to protect against allergic reactions when it is present in the gut.

Anaerostipes caccae is part of a class of bacteria that produce butyrate -- a short-chain fatty acid that is a crucial nutrient for establishing a healthy microbial community in the gut.

--IANS rt/mag/vm

( 358 Words)

2019-01-18-13:44:06 (IANS)

 
  LATEST COMMENTS ()
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
 
TRENDING TOPICS
 
 
CITY NEWS
MORE CITIES
 
 
 
MORE HEALTH NEWS
Kerala fails to get medics from reserved...
75-year-old woman delivers baby girl in ...
Antibody-based eye drop may treat dry ey...
Indian-origin doctors link bladder pill ...
Much needs to be done on health front: C...
Cats continue to gain weight till maturi...
More...
 
INDIA WORLD ASIA
BJP's Gandhi Sankalp Yatra to cover 6,50...
Those in power in Hry will be in Opposit...
Modi crosses 30 million followers on Ins...
Dutch King and Queen arrive in India for...
Isolate nations which aid and abet terro...
Stubble burning continues in Amritsar de...
More...    
 
 Top Stories
'Dolittle' Trailer: Robert Downey J... 
Here's how Megan Fox is celebrating... 
Ancient stories of brotherhood, Man... 
Significant work still to do on Bre... 
Telangana: Another RTC employee com... 
Mrinal Dutt: Digital platform opens... 
Ranbir Kapoor doesn't have baggage ... 
Mangaluru's Apeksha Kottary enters ...