Sunday, November 19, 2017
News

This drug may stall effects of alcohol on fetal brain

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

Washington D.C. [USA] | November 15, 2017 12:01:13 AM IST
 
An anti-inflammatory drug may have the potential to stall the damaging effects of alcohol on the fetal brain, according to a recent study.

Ibuprofen reduced neuroinflammation and behavioral signs of alcohol exposure in a rat model of fetal alcohol spectrum disorders (FASD).

The study was the first to directly link alcohol-induced inflammation in the hippocampus to cognitive impairment later in the life, said senior author Derick Lindquist from The Ohio State University.

The findings could have eventual implications reaching beyond fetal alcohol spectrum disorders, because neuroinflammation is a hallmark of many neurological diseases, he said.

Some of the animals in the study were exposed to alcohol four to nine days after birth - the scientific equivalent of the third trimester in a human pregnancy. Alcohol-exposed rats given ibuprofen had lower levels of inflammation in the brain than those given saline solution. Twenty-five days later they also exhibited enhanced long-term memory.

The research helps define the role of the brain's immune system and of inflammation in particular in the development of cognitive dysfunction after fetal alcohol exposure, Lindquist said.

While it's too soon to speculate on implications in humans, it could pave the way for future research into potential treatments for fetal alcohol spectrum disorders and other neurological problems, said lead author Molly Goodfellow.

The study appears in the journal Behavioural Brain Research. (ANI)

Watch News Videos

 
  LATEST COMMENTS (0)
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
TRENDING TOPICS
 
 
 
CITY NEWS
MORE CITIES
 
MORE HEALTH NEWS
Brain activity buffers against worsening...
Delhi's air quality improves, but stubbl...
This anti-malaria drug may be new weapon...
A key to stopping cancer in its tracks...
How to avoid germs in public washroom...
Parents' lifestyle can affect your healt...
More...
 
INDIA WORLD ASIA
Kovind stops in Assam en route to Arunac...
Tharoor draws flak for calling Miss Worl...
PM Modi, other national icons congratula...
Children who snore likelier to grow up i...
Ravinder Gosain murder: Three suspects s...
Manipur populace resolves to safeguard t...
More...    
 
 Top Stories
India all-rounder Deepti Sharma to ... 
CPI-M office stoned in Thiruvananth... 
Man arrested for creating fake webs... 
India takes up with South Africa ro... 
Bengali actress Rita Koiral dead... 
Afghanistan win U-19 Asia Cup crick... 
India takes up with South Africa ro... 
ISL: Second-half goals a lesson for...