Wednesday, May 23, 2018
News

Tweaking brain circuits may alleviate depression

   SocialTwist Tell-a-Friend    Print this Page   COMMENT

New York | Monday, 2017 7:45:04 PM IST
In a ray of hope for people suffering from social withdrawal and helplessness behaviour, scientists from the University of California San Diego have linked specific wiring in the brain to distinct behavioural symptoms of depression.

The team found brain circuits tied to feelings of despair and helplessness and were able to alleviate and even reverse such symptoms in mice.

"We took an approach of studying depression in the sense that different brain areas and circuits of the brain might mediate or contribute to very discrete aspects of depression," said study first-author Daniel Knowland, a UC San Diego graduate student.

"For example, brain area A might contribute to loss of appetite, brain area B to social withdrawal and so forth," he added in the study published in the journal Cell.

According to Assistant Professor Byungkook Lim, the results require much more study and evaluation to be applied to humans with depression but new research in animal models provides solid grounding.

"This is one of the first studies providing clear evidence showing that different brain circuitry is involved in different types of depressive behaviour with specific symptoms," said Lim.

Each area of the brain is different with distinct cell types and connectivity.

"If we can confirm that one area of circuitry is more involved in a particular symptom than another, we may eventually be able to treat a depression patient more efficiently than treating everyone the same way," Lim noted.

For the research, the scientists identified two populations of neurons in the brain's ventral pallidum region (part of the basal ganglia) as key to underlying depressive behaviour.

--IANS na/bg

( 277 Words)

2017-07-17-19:02:12 (IANS)

Watch News Videos

 
  LATEST COMMENTS (0)
POST YOUR COMMENT
Comments Not Available
 
POST YOUR COMMENT
 
TRENDING TOPICS
 
 
 
CITY NEWS
MORE CITIES
 
MORE HEALTH NEWS
Can Vitamin C cut harm of maternal smoki...
Dr Reddy's net drops by 19% in FY18 Bus...
Are humans influencing cancer in wild an...
Gestational diabetes may increase risk o...
Undiagnosed hypertension one of leading ...
SC to hear plea against NGT order on lea...
More...
 
INDIA WORLD ASIA
BJP to protest JD-S, Congress forming go...
Sterlite Copper expresses sorrow over vi...
BSF not first line of defence but first ...
BrahMos supersonic missile successfully ...
KCR sets target of June 2 for cheque dis...
CM Naidu demands PM Modi's answer on Spe...
More...    
 
 Top Stories
Venezuela expels US envoy... 
CSK beat SRH by 2 wickets to book r... 
BSF not first line of defence but f... 
Pentagon to appoint new US commande... 
BrahMos supersonic missile successf... 
Panama City shooting suspect barric... 
KCR sets target of June 2 for chequ... 
F-35 stealth fighter jets see first...